Had my instructor show me what to do. He said to make sure that the fine tuning screws are all set halfway when re-stringing - so not fully tightened and not fully lose. This gives you a lot more freedom when/if you need to fine tune.
Also stretch the strings out fully before locking the strings at the nut, this is really important because if the strings are not fully stretched then they will losen through playing making the locking system pointless.
Overall though I love the FR system, when it is used properly it is great.